Note: The author acknowledges, with great compassion, that this is a challenging topic for the many individuals who make the difficult decision to begin treatment with psychiatric medication. All patients must be given the most complete and accurate information about these medications, including: side effects (risk for dependence, violence, impulsivity, etc), the importance of properly
SAMe – S-Adenosylmethionine SAMe, a naturally occurring molecule synthesized by the “one-carbon cycle” which is dependent on B12 and folate, is a precursor to creatine, phosphatidylcholine, coQ10, carnitine, and myelin in addition to participating in production of neurotransmitters has been approved as a nutraceutical since the 1990s and prescribed in Europe for depression for three decades.
Schizophrenia is typically characterized by negative symptoms including apathy and impaired executive function while positive symptoms refer to delusions and hallucinations. Appreciating the role of B vitamins, and particularly folate, the metabolism of which is dictated by genetic variants such as MTHFR, the potential for meaningful intervention grows. 140 subjects were randomized to receive 400ug
What is postpartum depression? It depends who you ask. If you ask me, I’m likely to describe a number of potential contributors that can ultimately be tagged with the impressionist psychiatric descriptor of postpartum depression, anxiety, and psychosis. These terms tell us little to nothing about what’s actually going on in a woman’s body, yet
One of the most remarkable papers I have read in the psychiatric literature was about a 57 year old woman who was treated with months of both antipsychotic and antidepressant medications and given two rounds of electroconvulsive treatment before anyone bothered to check her vitamin B12 level. Her symptoms were years in the making including